Nicorandil 20 Tablet
Description
NICOROOT-20
Nicorandil 20 mg Tablets
Division: DIABGLYM
Composition
Each tablet contains:
Nicorandil IP — 20 mg
Excipients — q.s.
Colour: Approved colour used
Dosage form: Oral tablet
Product Description
NICOROOT-20 contains Nicorandil 20 mg, an advanced anti-anginal medication formulated for the prevention and long-term management of chronic stable angina pectoris and ischemic heart disease. Nicorandil possesses a unique dual mechanism of action by acting as both a nitrate donor and an ATP-sensitive potassium (KATP) channel opener, resulting in balanced arterial and venous vasodilation, improved coronary blood flow, and reduced myocardial oxygen demand.
Nicorandil is widely prescribed in cardiology for patients with chronic coronary artery disease, recurrent angina, microvascular angina, and patients who continue to experience anginal symptoms despite conventional anti-anginal therapy. It helps reduce the frequency of angina attacks, improve exercise tolerance, enhance myocardial perfusion, and decrease nitrate requirements.
NICOROOT-20 is particularly beneficial for patients requiring long-term anti-anginal therapy, improved coronary circulation, and additional anti-ischemic protection without significant negative effects on cardiac contractility.
Technical Knowledge of Nicorandil
Nicorandil combines nitrate-like vasodilatory properties with ATP-sensitive potassium channel activation. The nitrate component increases nitric oxide availability, activates guanylate cyclase, increases cyclic GMP levels, and relaxes vascular smooth muscle. The KATP channel opening effect causes hyperpolarization of vascular smooth muscle cells, producing additional arterial vasodilation and improved coronary microvascular circulation.
This dual mechanism reduces preload and afterload, improves coronary artery perfusion, enhances myocardial oxygen supply, and decreases myocardial oxygen consumption. Nicorandil also has favorable effects on coronary microcirculation and ischemic myocardial protection.
Mechanism of Action
Nicorandil releases nitric oxide, activates guanylate cyclase, increases cyclic GMP levels, opens ATP-sensitive potassium channels, relaxes vascular smooth muscle, dilates coronary and peripheral arteries, reduces preload and afterload, improves myocardial perfusion, and decreases myocardial oxygen demand.
Key Benefits
Helps prevent chronic angina attacks
Improves coronary blood flow and microcirculation
Reduces myocardial oxygen demand
Enhances exercise tolerance
Decreases frequency of anginal episodes
Provides dual anti-anginal mechanism
Supports long-term ischemic heart disease management
Suitable for chronic anti-anginal therapy under medical supervision
Clinical Applications
NICOROOT-20 is commonly prescribed for chronic stable angina pectoris, coronary artery disease, ischemic heart disease, refractory angina, microvascular angina, long-term anti-anginal therapy, and prevention of recurrent angina episodes.
Facts About Nicorandil
Nicorandil is a unique anti-anginal agent with both nitrate-donor and potassium channel opening properties. It has demonstrated efficacy in improving angina symptoms, exercise capacity, and coronary perfusion, and is particularly useful in patients with persistent angina despite standard anti-anginal therapy. Its beneficial effects on coronary microcirculation make it an important therapeutic option in chronic ischemic heart disease.
Key Facts
Dual-mechanism anti-anginal therapy
Nicorandil 20 mg for sustained angina prevention
Nitrate donor and potassium channel opener
Improves coronary blood flow and microvascular circulation
Reduces myocardial oxygen demand
Evidence-based cardiovascular therapy
Quality-assured pharmaceutical formulation
PCD Pharma Franchise Opportunity
NICOROOT-20 is an excellent product for PCD Pharma Franchise, Cardiology Franchise, and Cardio-Diabetic Franchise across India. The increasing prevalence of coronary artery disease, chronic angina, diabetes, hypertension, and ischemic heart disease creates strong prescription demand and long-term market potential for this formulation.
Why Choose NICOROOT-20 for PCD Pharma Franchise?
High prescription potential
Strong physician and cardiologist acceptance
Attractive monopoly franchise opportunity
Competitive pricing
Promotional support available
Visual aids and marketing inputs
Consistent product quality
Excellent repeat business potential
Third Party Manufacturing
Chemsroot Pharmaceutical offers Third Party Manufacturing of Nicorandil 20 mg Tablets with complete manufacturing support for pharmaceutical companies, marketers, exporters, and franchise businesses.
Our Third Party Manufacturing Services Include
Private label manufacturing
Contract manufacturing
Custom brand manufacturing
Loan license manufacturing
DCGI-compliant production
GMP-certified manufacturing
Batch manufacturing documentation
Product registration support
Customized packaging and artwork
Monopoly franchise packaging
Bulk manufacturing capability
Manufacturing Features
Pharmaceutical-grade raw materials
IP/BP/USP quality standards
In-process quality control
Finished product testing
Stability-oriented formulation
Moisture-controlled tablet manufacturing
Blister and Alu-Alu packaging options
NICOROOT-20 from DIABGLYM combines advanced dual-mechanism anti-anginal therapy, improved coronary perfusion, evidence-based cardiovascular care, and high-quality pharmaceutical manufacturing, making it an ideal product for physicians, cardiologists, PCD Pharma Franchise partners, and Third Party Manufacturing clients seeking a reliable Nicorandil formulation.
